In "To Kill a Mockingbird," what is the symbolic significance that nobody at the Radley house heeded Calpurnia's warning? This question is...

When Jem reported to Cal that ol' Tim Johnson was wobbling
suspiciously down the street, Calpurnia came out to see for herself. She recognized
immediately that the dog had rabies and quickly alerted the neighborhood. First she
called Atticus and then she told the town operator, Eula May, to notify "Miss Rachel and
Miss Stephanie Crawford and whoever's got a phone on this street" that "a mad dog's
comin'." She then ran to the Radley's house to give them the news since they had no
phone. She "banged on the door" and yelled for the Radleys, but she received no
response. The significance of this was simple: Nathan Radley was probably not at home,
and Boo never came outside. The madness outside displayed by Tim Johnson was dealt with
in a different manner by the Radleys, whose madness was contained within the four walls
of the home.